The role of amp-activated protein kinase (AMPK) in the signaling pathway related to the ketogenic diet during resistance training
پذیرفته شده برای پوستر
شناسه دیجیتال (DOI): 10.48308/ths.2024.9875
کد مقاله : 1207-THS
نویسندگان
1دانشجوی کارشناسی ارشد+فیزیولوژی ورزشی/تغذیه ورزشی+علوم ورزشی+رازی کرمانشاه+کرمانشاه
2استادیار فیزیولوژی ورزش، گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه رازی، کرمانشاه، ایران
چکیده
The ketogenic diet has gained significant attention in recent years due to
its potential benefits for weight loss, metabolic health, and athletic
performance. Resistance training is a popular exercise modality that
aims to increase muscle mass and strength. However, the interaction
between the ketogenic diet and resistance training is not well
understood. This study review aims to explore the role of AMP-activated
protein kinase (AMPK) in the signaling pathway related to the ketogenic
diet during resistance training. AMPK is a key regulator of cellular
energy homeostasis and is activated in response to low energy
availability, such as during periods of fasting or carbohydrate restriction.
The ketogenic diet, characterized by high fat, low carbohydrate intake,
induces a state of nutritional ketosis where the body primarily relies on
ketone bodies for fuel instead of glucose. This metabolic shift has been
shown to activate AMPK, which in turn regulates various downstream
signaling pathways involved in energy metabolism, protein synthesis,
and muscle adaptation. The search results indicate that the effects of the
ketogenic diet on resistance training adaptations are complex. While the
ketogenic diet may have potential benefits for weight loss and body
composition, it may also attenuate muscle mass gains due to reduced
carbohydrate availability. AMPK activation during the ketogenic diet may
play a role in mediating these effects by modulating protein synthesis,
autophagy, and mitochondrial biogenesis. However, it is important to
note that the specific signaling pathway related to the ketogenic diet
during resistance training and its interaction with AMPK is not explicitly
mentioned in the search results. Further research is needed to elucidate
the molecular mechanisms underlying the interaction between the
ketogenic diet, resistance training, and AMPK signaling.
In conclusion, this study review highlights the potential role of AMPK in
the signaling pathway related to the ketogenic diet during resistance
training. While the ketogenic diet may have both positive and negative
effects on resistance training adaptations, AMPK activation may be a
key mediator of these effects. Further research is warranted to better
understand the molecular mechanisms involved and to optimize the
integration of the ketogenic diet and resistance training for optimal
performance and muscle adaptation.
its potential benefits for weight loss, metabolic health, and athletic
performance. Resistance training is a popular exercise modality that
aims to increase muscle mass and strength. However, the interaction
between the ketogenic diet and resistance training is not well
understood. This study review aims to explore the role of AMP-activated
protein kinase (AMPK) in the signaling pathway related to the ketogenic
diet during resistance training. AMPK is a key regulator of cellular
energy homeostasis and is activated in response to low energy
availability, such as during periods of fasting or carbohydrate restriction.
The ketogenic diet, characterized by high fat, low carbohydrate intake,
induces a state of nutritional ketosis where the body primarily relies on
ketone bodies for fuel instead of glucose. This metabolic shift has been
shown to activate AMPK, which in turn regulates various downstream
signaling pathways involved in energy metabolism, protein synthesis,
and muscle adaptation. The search results indicate that the effects of the
ketogenic diet on resistance training adaptations are complex. While the
ketogenic diet may have potential benefits for weight loss and body
composition, it may also attenuate muscle mass gains due to reduced
carbohydrate availability. AMPK activation during the ketogenic diet may
play a role in mediating these effects by modulating protein synthesis,
autophagy, and mitochondrial biogenesis. However, it is important to
note that the specific signaling pathway related to the ketogenic diet
during resistance training and its interaction with AMPK is not explicitly
mentioned in the search results. Further research is needed to elucidate
the molecular mechanisms underlying the interaction between the
ketogenic diet, resistance training, and AMPK signaling.
In conclusion, this study review highlights the potential role of AMPK in
the signaling pathway related to the ketogenic diet during resistance
training. While the ketogenic diet may have both positive and negative
effects on resistance training adaptations, AMPK activation may be a
key mediator of these effects. Further research is warranted to better
understand the molecular mechanisms involved and to optimize the
integration of the ketogenic diet and resistance training for optimal
performance and muscle adaptation.
کلیدواژه ها
Title
The role of amp-activated protein kinase (AMPK) in the signaling
pathway related to the ketogenic diet during resistance training
Authors
amirhosein yaeghobi, rastegar Hoseini
Abstract
The ketogenic diet has gained significant attention in recent years due to
its potential benefits for weight loss, metabolic health, and athletic
performance. Resistance training is a popular exercise modality that
aims to increase muscle mass and strength. However, the interaction
between the ketogenic diet and resistance training is not well
understood. This study review aims to explore the role of AMP-activated
protein kinase (AMPK) in the signaling pathway related to the ketogenic
diet during resistance training. AMPK is a key regulator of cellular
energy homeostasis and is activated in response to low energy
availability, such as during periods of fasting or carbohydrate restriction.
The ketogenic diet, characterized by high fat, low carbohydrate intake,
induces a state of nutritional ketosis where the body primarily relies on
ketone bodies for fuel instead of glucose. This metabolic shift has been
shown to activate AMPK, which in turn regulates various downstream
signaling pathways involved in energy metabolism, protein synthesis,
and muscle adaptation. The search results indicate that the effects of the
ketogenic diet on resistance training adaptations are complex. While the
ketogenic diet may have potential benefits for weight loss and body
composition, it may also attenuate muscle mass gains due to reduced
carbohydrate availability. AMPK activation during the ketogenic diet may
play a role in mediating these effects by modulating protein synthesis,
autophagy, and mitochondrial biogenesis. However, it is important to
note that the specific signaling pathway related to the ketogenic diet
during resistance training and its interaction with AMPK is not explicitly
mentioned in the search results. Further research is needed to elucidate
the molecular mechanisms underlying the interaction between the
ketogenic diet, resistance training, and AMPK signaling.
In conclusion, this study review highlights the potential role of AMPK in
the signaling pathway related to the ketogenic diet during resistance
training. While the ketogenic diet may have both positive and negative
effects on resistance training adaptations, AMPK activation may be a
key mediator of these effects. Further research is warranted to better
understand the molecular mechanisms involved and to optimize the
integration of the ketogenic diet and resistance training for optimal
performance and muscle adaptation.
its potential benefits for weight loss, metabolic health, and athletic
performance. Resistance training is a popular exercise modality that
aims to increase muscle mass and strength. However, the interaction
between the ketogenic diet and resistance training is not well
understood. This study review aims to explore the role of AMP-activated
protein kinase (AMPK) in the signaling pathway related to the ketogenic
diet during resistance training. AMPK is a key regulator of cellular
energy homeostasis and is activated in response to low energy
availability, such as during periods of fasting or carbohydrate restriction.
The ketogenic diet, characterized by high fat, low carbohydrate intake,
induces a state of nutritional ketosis where the body primarily relies on
ketone bodies for fuel instead of glucose. This metabolic shift has been
shown to activate AMPK, which in turn regulates various downstream
signaling pathways involved in energy metabolism, protein synthesis,
and muscle adaptation. The search results indicate that the effects of the
ketogenic diet on resistance training adaptations are complex. While the
ketogenic diet may have potential benefits for weight loss and body
composition, it may also attenuate muscle mass gains due to reduced
carbohydrate availability. AMPK activation during the ketogenic diet may
play a role in mediating these effects by modulating protein synthesis,
autophagy, and mitochondrial biogenesis. However, it is important to
note that the specific signaling pathway related to the ketogenic diet
during resistance training and its interaction with AMPK is not explicitly
mentioned in the search results. Further research is needed to elucidate
the molecular mechanisms underlying the interaction between the
ketogenic diet, resistance training, and AMPK signaling.
In conclusion, this study review highlights the potential role of AMPK in
the signaling pathway related to the ketogenic diet during resistance
training. While the ketogenic diet may have both positive and negative
effects on resistance training adaptations, AMPK activation may be a
key mediator of these effects. Further research is warranted to better
understand the molecular mechanisms involved and to optimize the
integration of the ketogenic diet and resistance training for optimal
performance and muscle adaptation.
Keywords
Key Words: AMPK, Exercise, Metabolic Health, Diet