Purpose: The purpose of this research was to investigate the effect of the order of resistance activity intensity on cell damage indicators and acute phase proteins in inactive training men.
Methodology: 20 men with age range of 22-30 years without history of resistance training were selected by targeted and accessible sampling and randomly divided into two groups of low to high intensity resistance training (10 people) and high to low intensity resistance training group. (10 people) were divided. A single-session resistance activity included movements for the upper limb, including chest press, underarm stretch with a pulley, forearm and back arm with a barbell, and lower limb movements including squat, back leg, and front leg with a machine for 45 minutes. Before and after the exercise protocol, venous blood sampling was done and the concentration of creatine kinase (CK) and lactate dehydrogenase (LDH), haptoglobin and C-reactive protein (CRP) were measured using an autoanalyzer. One-way analysis of variance and Tukey's post hoc test were used to analyze the data.
Findings: The research results showed that both resistance training protocols lead to a significant increase in the concentrations of CK and LDH, haptoglobin and CRP in the post-test. Comparison between groups did not show significant differences in the concentrations of CK and LDH, haptoglobin and CRP between the two groups.
Conclusion: Although our results showed that the concentration of CK and LDH enzymes as well as CRP and haptoglobin show a significant increase after resistance training in low-to-high intensity and high-to-low intensity, but the order of the intensity of resistance activity affects cell damage factors. And acute phase rabies protein is not effective. Therefore, this issue cannot be considered as a limiting factor in the design of resistance exercises.