Introduction: Technology has played an important role in transforming people's lives. The use of technology among society has greatly increased. With the sudden increase in the use of smartphones in recent times, musculoskeletal discomfort has increased dramatically. Neck pain is one of the most common musculoskeletal disorders among smartphone users. The aim of the present study is neck pain and disorders of the upper limbs and its relationship with the amount of use of smartphones among office workers. The statistical population of the research was conducted on 107 employees in the age group of 25 to 55 years. The employees were selected based on the entry and exit criteria. Inclusion criteria: Both men and women in the age group of 25 to 55 years who used mobile phones were included in the study and exclusion criteria: 1. Congenital abnormalities of the spine and upper limbs. 2. Impact on the neck and upper limbs. 3. Recent spine and/or upper extremity surgery. 4. Any neurological disorder; And after explaining the purpose and nature of the study, written consent was obtained from the subjects. A total of 107 people were screened for the study using random sampling method. Three self-report questionnaires (researcher-made questionnaires of neck disability index, arm, shoulder and hand disability scale) were presented to the participants. The participants were asked to fill in the information requested in the questionnaires and return them to the researcher. The data was analyzed using SPSS 24. To analyze the results, percentage analysis and correlation coefficient were used and statistically significant criteria were determined as p ≤ 0.05. Findings: The prevalence of neck and upper limb discomfort among employees who used mobile phones was 89.71%. Of these, 88.78% of people complained about shoulder discomfort, 14.95% elbow discomfort and 28.97% hand/wrist discomfort. Statistically, there is a significant relationship between neck disability and the hours of working on the phone per day (r = 0.89, p = 0.01), the hours of working on the phone in the last week (r = 0.35, p = 0.08) and rest time. (r = 0.14, p = 0.13) There was no statistical non-significant relationship for arm, shoulder and hand disabilities with working hours on the phone per day (r = 0.03, p = 0.69), working hours by phone in the last week (r = 0.11, p = 0.25) and rest time (r = 0.42, p = 0.07). Conclusion: The results showed that the prevalence of shoulder discomfort is higher than that of the elbow. and hand/wrist observed among employees.