Introduction: the aim of this study was to investigate the effect of aerobic training with cinnamon extract on APO-a and lipid profile in insulin-resistant rats. Methodology: Forty-eight male Wistar rats were randomly selected as subjects. For insulin-resistant rats fructose solution 10% was used for 5 weeks. The mice were divided randomly into four groups. (1- Control, 2- training, Group, 3- Extract Group, 4. Training - Extract). Then practice groups for 8 weeks, 5 days per week exercise program were implemented. Trading phase (first week), mice every day for 10-15 minutes at a speed of 10 meters per minute and rodents walked on a treadmill. At the overload phase (weeks two to four), the mice for 15 min at a speed of 12 meters per minute they walk, And the intensity and duration of activity increased gradually over a period of 3 weeks to reach the final set for each group. Phase maintain or stabilize, fifth to eighth week for 4 weeks, rats with severe determine the extent of 28 meters per minute, equivalent to 75-80% of maximum oxygen uptake on a treadmill for 60 minutes running, In all the steps above zero degrees incline. In groups each sample extract 200 mg per kilogram of body weight (5.0 mL) solution obtained was injected daily. One-way analysis of variance was used to test the hypothesis.
Results: Training and training with cinnamon extract significantly increased serum APO-A1 in comparison with the control group. Also Training and training with cinnamon significantly reduced LDL, TC, TG and increased HDL.
Discussions: In general, the results of this study indicate the beneficial effects of exercise training and consumption of cinnamon extract on cardiovascular risk factors in insulin- resistant rats, and these non-pharmacological methods can be used to control diabetes.