Introduction: Child development experts believe that play is the main part of children's lives. Children show their greatest power and energy while playing. The game is a way that, while creating joy and happiness in children, it also develops motor development in them. Rhythmic games are one of the favorite training methods of children and teenagers. Since performing these movements is often accompanied by music and is done in groups, people are more motivated to participate in them, and children and teenagers show a great desire to perform these types of physical movements for this reason. Purpose: The purpose of this research was a cross-cultural study to investigate the effect of 16 sessions of rhythmic exercises on motor skills, social development and self-esteem of children with developmental coordination disorder in Iran and Turkey. Methodology: The statistical population of this research included 8-10-year-old children who had developmental coordination disorder and were studying in the schools of Tehran (Region 5) and the European part of Istanbul during the year 1400-1401. 40 people were selected from among the mentioned statistical population and participated in rhythmic exercises randomly in four groups of 10 people (two groups in Tehran and two groups in Istanbul). Data analysis was done using SPSS version 23 software and three-way ANOVA. Results: The results of this research showed that rhythmic exercises were significant on motor skills, social development and self-esteem, so we conclude that rhythmic exercises as an effective, dynamic and attractive training method to create motivation and desire in children with coordination disorder. It is developmental and has been able to have more positive effects on improving social skills, self-esteem and motor skills of children with developmental coordination disorder. Also, based on the findings of this research, it was found that the cultural difference and the type of music was not an influencing factor on the factors investigated in this research.