Introduction: The purpose of this study was to investigate the effect of moderate intensity aerobic exercise with cannabis supplementation on weight changes in obese rats fed a high-fat diet
materials and methods : In this experimental study, 40 male Wistar rats were randomly divided into 5 groups: (1) normal, (2) high-fat, (3) exercise, (4) supplement, and (5) exercise+supplement, and except for group 1, the rest They were subjected to a high-fat diet (40% fat, 40% carbohydrates and 20% protein) for 16 weeks. The exercise program was performed for 6 weeks of aerobic exercise with moderate intensity, for 5 consecutive days a week with an increasing process on the treadmill (without incline). Mice were gavage with Lactobacillus bifidus supplement in the amount of 1 ml each time. Mice were weighed twice a week.
The results showed that other groups had 35-40% weight gain compared to group 1. After the intervention, group 2 gained about 5% weight, group 3 lost 2% weight, and groups 4 and 5 had almost no weight changes. Comparing the average weight changes in 5 groups showed that the highest weight gain was in group 2, the lowest in group 1, group 4 was less than groups 3 and 5, and groups 3 and 5 were equal after the intervention.
Conclusion: Following a normal and regular diet does not cause significant weight changes. Improper nutritional behavior and excessive consumption of fat (calories) increase the process of obesity and its difficult adjustment despite taking supplements and exercising. The current research showed that exercise and supplements together lead to weight loss of about 13% and supplements and exercise each alone about 10% compared to a high-fat diet.